abstract：INTRODUCTION:With limited funds available, meeting global health targets requires countries to both mobilize and prioritize their health spending. Within this context, countries have recognized the importance of allocating funds for HIV as efficiently as possible to maximize impact. Over the past six years, the governm...

journal_title：Journal of the International AIDS Society

authors： Stuart RM,Grobicki L,Haghparast-Bidgoli H,Panovska-Griffiths J,Skordis J,Keiser O,Estill J,Baranczuk Z,Kelly SL,Reporter I,Kedziora DJ,Shattock AJ,Petravic J,Hussain SA,Grantham KL,Gray RT,Yap XF,Martin-Hughes R,Bened

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:The HIV Strategy in New South Wales (NSW) Australia aims to virtually eliminate HIV transmission by 2020. We estimated the 2016 HIV diagnosis and care cascade for the state of NSW, with a focus on introducing population-based data to improve data quality and assess progress towards the UNAIDS 90-90-90 targ...

journal_title：Journal of the International AIDS Society

authors： Keen P,Gray RT,Telfer B,Guy R,Schmidt HM,Whittaker B,Holden J,Holt M,Kelleher A,Wilson D,Callander D,Cooper DA,Prestage G,Selvey C,Grulich AE,NSW HIV Prevention Partnership Project.

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:In 2016, the Global Health Sector Strategy (GHSS) on viral hepatitis called for elimination of viral hepatitis as a major public health threat by 2030 (i.e. 90% reduction in incidence and 65% in mortality). In 2017, WHO's first-ever Global Hepatitis Report presented the baseline values for each of the core...

journal_title：Journal of the International AIDS Society

authors： Hutin YJ,Bulterys M,Hirnschall GO

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:The World Health Organization targets for hepatitis C virus (HCV) elimination include a 90% reduction in new infections by 2030. Our objective is to review the modelling evidence and cost data surrounding feasibility of HCV elimination among people living with HIV (PLWH), and identify likely components for...

journal_title：Journal of the International AIDS Society

authors： Martin NK,Boerekamps A,Hill AM,Rijnders BJA

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:Worldwide, 71 million people are infected with hepatitis C virus (HCV), which, without treatment, can lead to liver failure or hepatocellular carcinoma. HCV co-infection increases liver- and AIDS-related morbidity and mortality among HIV-positive people, despite ART. A 12-week course of HCV direct-acting a...

journal_title：Journal of the International AIDS Society

authors： Grillon C,Krishtel PR,Mellouk O,Basenko A,Freeman J,Mendão L,Andrieux-Meyer I,Morin S

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:The Amsterdam PrEP project is a prospective, open-label demonstration study at a large sexually transmitted infection (STI) clinic. We examined the uptake of PrEP; the baseline characteristics of men who have sex with men (MSM) and transgender persons initiating PrEP; their choices of daily versus event-dr...

journal_title：Journal of the International AIDS Society

authors： Hoornenborg E,Achterbergh RC,van der Loeff MFS,Davidovich U,van der Helm JJ,Hogewoning A,van Duijnhoven YT,Sonder GJ,de Vries HJ,Prins M,Amsterdam PrEP Project team in the HIV Transmission Elimination AMsterdam Initiative.

更新日期：2018-03-01 00:00:00

abstract：INTRODUCTION:Guidelines regarding antiretroviral therapy (ART) initiation in HIV infection have varied over time, with the 2015 World Health Organization recommendation suggesting ART initiation at the time of diagnosis regardless of CD4 T-cell counts. Herein, we investigated the influence of socio-demographic and clin...

journal_title：Journal of the International AIDS Society

authors： Mehraj V,Cox J,Lebouché B,Costiniuk C,Cao W,Li T,Ponte R,Thomas R,Szabo J,Baril JG,Trottier B,Côté P,LeBlanc R,Bruneau J,Tremblay C,Routy JP,Montreal Primary HIV-Infection Study Group.

更新日期：2018-02-01 00:00:00

abstract：INTRODUCTION:Outbreaks of hepatitis C virus (HCV) infections among HIV-positive men who have sex with men (MSM) have been observed globally. Using a multi-modelling approach we estimate the time and number of direct-acting antiviral treatment courses required to achieve an 80% reduction in HCV prevalence among HIV-posi...

journal_title：Journal of the International AIDS Society

authors： Scott N,Stoové M,Wilson DP,Keiser O,El-Hayek C,Doyle J,Hellard M

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:Optimal adherence to antiretroviral therapy is closely related with suppression of the HIV viral load in plasma, slowing disease progression and decreasing HIV transmission rates. Despite its importance, the estimated proportion of people living with HIV in Latin America and the Caribbean with optimal adhe...

journal_title：Journal of the International AIDS Society

authors： Costa JM,Torres TS,Coelho LE,Luz PM

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:The success of HIV treatment programmes globally has resulted in children with perinatally acquired HIV reaching adolescence in large numbers. The number of adolescents living with HIV is growing further due to persisting high HIV incidence rates among adolescents in low- and middle-income settings, partic...

journal_title：Journal of the International AIDS Society

authors： Marcus R,Ferrand RA,Kranzer K,Bekker LG

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:The objective of this commentary is to review considerations for implementing routine viral load (VL) monitoring programmes for HIV-infected infants and children living in low- and middle-income countries (LMIC). Since 2013, the World Health Organization (WHO) guidelines recommend VL testing as the preferr...

journal_title：Journal of the International AIDS Society

authors： Arpadi SM,Shiau S,De Gusmao EP,Violari A

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:Globally, young gay, bisexual and other men who have sex with men (gbMSM) continue to experience disproportionately high rates of HIV and other sexually transmitted and blood-borne infections (STBBIs). As such, there are strong public health imperatives to evaluate innovative prevention, treatment and care...

journal_title：Journal of the International AIDS Society

authors： Knight R,Karamouzian M,Salway T,Gilbert M,Shoveller J

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:Infection with HIV subtype A has been associated with poorer neurocognitive outcomes compared to HIV subtype D in Ugandan children not eligible for antiretroviral therapy (ART). In this study, we sought to determine whether subtype-specific differences are also observed among children receiving ART. MATER...

journal_title：Journal of the International AIDS Society

authors： Bangirana P,Ruel TD,Boivin MJ,Pillai SK,Giron LB,Sikorskii A,Banik A,Achan J

更新日期：2017-10-01 00:00:00

abstract：INTRODUCTION:Oral pre-exposure prophylaxis (PrEP) is a promising new prevention approach for those most at risk of HIV infection. However, there are concerns that behavioural disinhibition, specifically reductions in condom use, might limit PrEP's protective effect. This study uses the case of female sex workers (FSWs)...

journal_title：Journal of the International AIDS Society

authors： Grant H,Mukandavire Z,Eakle R,Prudden H,B Gomez G,Rees H,Watts C

更新日期：2017-09-20 00:00:00

abstract：INTRODUCTION:Countries in the West and Central African regions struggle to offer quality HIV care at scale, despite HIV prevalence being relatively low. In these challenging operating environments, basic health care needs are multiple, systems are highly fragile and conflict disrupts health care. Médecins Sans Frontièr...

journal_title：Journal of the International AIDS Society

authors： Ssonko C,Gonzalez L,Mesic A,da Fonseca MS,Achar J,Safar N,Martin B,Wong S,Casas EC

更新日期：2017-07-21 00:00:00

abstract：INTRODUCTION:Poor access of lesbian, gay, bisexual and transgender (LGBT) people to healthcare providers with clinical and cultural competency contributes to health inequalities between heterosexual/cisgender and LGBT people. This systematic review assesses the effect of educational curricula and training for healthcar...

journal_title：Journal of the International AIDS Society

authors： Sekoni AO,Gale NK,Manga-Atangana B,Bhadhuri A,Jolly K

更新日期：2017-07-19 00:00:00

abstract：INTRODUCTION:Transactional sex is a structural driver of HIV for women and girls in sub-Saharan Africa. In transactional relationships, sexual and economic obligations intertwine and may have positive and negative effects on women's financial standing and social status. We conducted a clinic-based survey with pregnant ...

journal_title：Journal of the International AIDS Society

authors： Fielding-Miller R,Dunkle KL,Hadley C,Cooper HL,Windle M

更新日期：2017-07-18 00:00:00

abstract：INTRODUCTION:Modern combined antiretroviral therapies (cART) allow to effectively suppress HIV-1 viral load, with the 90% virologic success rate, meeting the WHO target in most clinical settings. The aim of this study was to analyse antiretroviral treatment efficacy in Poland and to identify variables associated with v...

journal_title：Journal of the International AIDS Society

authors： Parczewski M,Siwak E,Leszczyszyn-Pynka M,Cielniak I,Burkacka E,Pulik P,Witor A,Muller K,Zasik E,Grzeszczuk A,Jankowska M,Lemańska M,Olczak A,Grąbczewska E,Szymczak A,Gąsiorowski J,Szetela B,Bociąga-Jasik M,Skwara P,

更新日期：2017-07-17 00:00:00

abstract：INTRODUCTION:Decentralization of HIV care for children has been recommended to improve paediatric outcomes by making antiretroviral treatment (ART) more accessible. We documented outcomes of children transferred after initiating ART at a large tertiary hospital in the Eastern Cape of South Africa. METHODS:Electronic m...

journal_title：Journal of the International AIDS Society

authors： Teasdale CA,Sogaula N,Yuengling KA,Peters ZJ,Mutiti A,Pepeta L,Abrams EJ

更新日期：2017-06-28 00:00:00

abstract：BACKGROUND:Traditional medication adherence measures do not account for the pharmacokinetic (PK) properties of the drugs, potentially misrepresenting true therapeutic exposure. METHODS:In a population of HIV-infected Kenyan children on antiretroviral therapy including nevirapine (NVP), we used a one-compartment model ...

journal_title：Journal of the International AIDS Society

authors： Tu W,Nyandiko WM,Liu H,Slaven JE,Scanlon ML,Ayaya SO,Vreeman RC

更新日期：2017-06-15 00:00:00

abstract：:[This corrects the article DOI: 10.7448/IAS.20.01/21317.]. ...

journal_title：Journal of the International AIDS Society

authors：

更新日期：2017-06-02 00:00:00

abstract：INTRODUCTION:The HIV epidemics in the Caribbean, Central America and South America (CCASA), Eastern Europe (EE) and Asia and Pacific (AP) regions are diverse epidemics affecting different key populations in predominantly middle-income countries. This narrative review describes the populations of HIV-positive youth appr...

journal_title：Journal of the International AIDS Society

authors： Bailey H,Cruz MLS,Songtaweesin WN,Puthanakit T

更新日期：2017-05-16 00:00:00

abstract：INTRODUCTION:Lopinavir/ritonavir-based antiretroviral therapy (ART) is recommended for all HIV-infected children less than three years. However, little is known about its field implementation and effectiveness in West Africa. We assessed the 12-month response to lopinavir/ritonavir-based antiretroviral therapy in a coh...

journal_title：Journal of the International AIDS Society

authors： Amani-Bosse C,Dahourou DL,Malateste K,Amorissani-Folquet M,Coulibaly M,Dattez S,Emieme A,Barry M,Rouzioux C,N'gbeche S,Yonaba C,Timité-Konan M,Mea V,Ouédraogo S,Blanche S,Meda N,Seguin-Devaux C,Leroy V

更新日期：2017-04-25 00:00:00

abstract：INTRODUCTION:HIV and syphilis testing rates remain low among men who have sex with men (MSM) in low- and middle-income countries (LMICs). Community engagement has been increasingly used to promote HIV testing among key populations in high-income countries, often in settings with stronger civil society. This study aimed...

journal_title：Journal of the International AIDS Society

authors： Zhang TP,Liu C,Han L,Tang W,Mao J,Wong T,Zhang Y,Tang S,Yang B,Wei C,Tucker JD

更新日期：2017-04-03 00:00:00

abstract：INTRODUCTION:Although individual HIV rapid diagnostic tests (RDTs) show good performance in evaluations conducted by WHO, reports from several African countries highlight potentially significant performance issues. Despite widespread use of RDTs for HIV diagnosis in resource-constrained settings, there has been no syst...

journal_title：Journal of the International AIDS Society

authors： Kosack CS,Page AL,Beelaert G,Benson T,Savane A,Ng'ang'a A,Andre B,Zahinda JB,Shanks L,Fransen K

更新日期：2017-03-24 00:00:00

abstract：INTRODUCTION:People living with HIV (PLHIV) have the right to exercise voluntary choices about their health, including their reproductive health. This commentary discusses the integral role that family planning (FP) plays in helping PLHIV, including those in serodiscordant relationships, achieve conception safely. The ...

journal_title：Journal of the International AIDS Society

authors： Mason J,Medley A,Yeiser S,Nightingale VR,Mani N,Sripipatana T,Abutu A,Johnston B,Watts DH

更新日期：2017-03-08 00:00:00

abstract：INTRODUCTION:Policies for rationing antiretroviral therapy (ART) have been subject to on-going ethical debates. Introduced in Malawi in 2011, Option B+ prioritized HIV-positive pregnant women for lifelong ART regardless of the underlying state of their immune system, shifting the logic of allocation away from medical e...

journal_title：Journal of the International AIDS Society

authors： Yeatman S,Trinitapoli J

更新日期：2017-03-08 00:00:00

abstract：INTRODUCTION:Almost from the beginning of the HIV epidemic in 1981, an association with tuberculosis (TB) was recognized. This association between HIV and TB co-infection has been particularly evident amongst prisoners. However, despite this, few studies of TB in prisons have stratified results by HIV status. Given the...

journal_title：Journal of the International AIDS Society

authors： Edge CL,King EJ,Dolan K,McKee M

更新日期：2016-11-15 00:00:00

abstract：INTRODUCTION:Pre-treatment HIV drug resistance (PDR) is an increasing problem in sub-Saharan Africa. Children are an especially vulnerable population to develop PDR given that paediatric second-line treatment options are limited. Although monitoring of PDR is important, data on the paediatric prevalence in sub-Saharan ...

journal_title：Journal of the International AIDS Society

authors： Boerma RS,Boender TS,Sigaloff KC,Rinke de Wit TF,van Hensbroek MB,Ndembi N,Adeyemo T,Temiye EO,Osibogun A,Ondoa P,Calis JC,Akanmu AS

更新日期：2016-11-10 00:00:00

abstract：INTRODUCTION:Young women aged 15 to 24 years in sub-Saharan Africa continue to be disproportionately affected by HIV. A growing number of studies have suggested that the practice of transactional sex may in part explain women's heightened risk, but evidence on the association between transactional sex and HIV has not y...

journal_title：Journal of the International AIDS Society

authors： Wamoyi J,Stobeanau K,Bobrova N,Abramsky T,Watts C

更新日期：2016-11-02 00:00:00

abstract：INTRODUCTION:Changes in combination antiretroviral therapy (cART) throughout childhood challenge the continuity of paediatric HIV treatment. This study aimed to evaluate the prevalence of treatment interruption (TI), including lamivudine (3TC) monotherapy, and the relationship of TI to virologic and immunologic paramet...

journal_title：Journal of the International AIDS Society

authors： Rakhmanina N,Lam KS,Hern J,Young HA,Walters A,Castel AD

更新日期：2016-10-27 00:00:00

abstract：INTRODUCTION:Of the two million new HIV infections in adults in 2014, 70% occurred in sub-Saharan Africa. Several African countries have already approved guidelines for pre-exposure prophylaxis (PrEP) for individuals at substantial risk of HIV as part of combination HIV prevention but key questions remain about how to ...

journal_title：Journal of the International AIDS Society

authors： Cowan FM,Delany-Moretlwe S,Sanders EJ,Mugo NR,Guedou FA,Alary M,Behanzin L,Mugurungi O,Bekker LG

更新日期：2016-10-18 00:00:00

abstract：INTRODUCTION:Qualitative research on antiretroviral therapy (ART) adherence interventions can provide a deeper understanding of intervention facilitators and barriers. This systematic review aims to synthesize qualitative evidence of interventions for improving ART adherence and to inform patient-centred policymaking. ...

journal_title：Journal of the International AIDS Society

authors： Ma Q,Tso LS,Rich ZC,Hall BJ,Beanland R,Li H,Lackey M,Hu F,Cai W,Doherty M,Tucker JD

更新日期：2016-10-17 00:00:00

abstract：INTRODUCTION:Critical technological advances have yielded a toolkit of HIV prevention strategies. This literature review sought to provide contextual and historical reflection needed to bridge the conceptual gap between clinical efficacy and community effectiveness (i.e. knowledge and usage) of existing HIV prevention ...

journal_title：Journal of the International AIDS Society

authors： Parker RG,Perez-Brumer A,Garcia J,Gavigan K,Ramirez A,Milnor J,Terto V Jr

更新日期：2016-09-30 00:00:00

abstract：INTRODUCTION:Vaginal tenofovir (TFV) 1% gel may reduce incident HIV-1 and herpes simplex virus 2 infection. Pregnancy may increase risk of HIV acquisition, and incident HIV in pregnancy potentiates perinatal HIV transmission. Our objective was to investigate the safety and pharmacokinetics of seven days of TFV 1% vagin...

journal_title：Journal of the International AIDS Society

authors： Beigi RH,Noguchi LM,Montgomery E,Biggio J,Hendrix CW,Marzinke MA,Dai JY,Pan J,Kunjara Na Ayudhya R,Schwartz JL,Isaacs K,Piper JM,Watts DH

更新日期：2016-09-21 00:00:00

abstract：INTRODUCTION:In response to the increasing burden of HIV, the Ugandan government has employed different service delivery models since 2004 that aim to reduce costs and remove barriers to accessing HIV care. These models include community-based approaches to delivering antiretroviral therapy (ART) and delegating tasks t...

journal_title：Journal of the International AIDS Society

authors： Vu L,Waliggo S,Zieman B,Jani N,Buzaalirwa L,Okoboi S,Okal J,Borse NN,Kalibala S

更新日期：2016-07-20 00:00:00

abstract：INTRODUCTION:Sex workers, people who use drugs, men who have sex with men, women who have sex with women and transgender people in South Africa frequently experience high levels of stigma, abuse and discrimination. Evidence suggests that such abuse is sometimes committed by police officers, meaning that those charged w...

journal_title：Journal of the International AIDS Society

authors： Scheibe A,Howell S,Müller A,Katumba M,Langen B,Artz L,Marks M

更新日期：2016-07-18 00:00:00

abstract：INTRODUCTION:Transgender women are the population most vulnerable to HIV in Latin America, with prevalence between 18 and 38%. Although the region has improved antiretroviral coverage, there is an urgent need to strengthen HIV prevention for key populations to meet regional targets set by governments. We conducted an a...

journal_title：Journal of the International AIDS Society

authors： Silva-Santisteban A,Eng S,de la Iglesia G,Falistocco C,Mazin R

更新日期：2016-07-17 00:00:00

abstract：INTRODUCTION:Although hepatitis C virus (HCV) screening is recommended for all HIV-infected patients initiating antiretroviral therapy, data on epidemiologic characteristics of HCV infection in resource-limited settings are scarce. METHODS:We searched PubMed and EMBASE for studies assessing the prevalence of HCV infec...

journal_title：Journal of the International AIDS Society

authors： Azevedo TC,Zwahlen M,Rauch A,Egger M,Wandeler G

更新日期：2016-06-09 00:00:00

abstract：INTRODUCTION:HIV prevalence is declining in key populations in Armenia including in people who inject drugs (PWID), men who have sex with men, prison inmates, and female sex workers (FSWs); however, prevalence is increasing among Armenians who seasonally migrate to work in countries with higher HIV prevalence, primaril...

journal_title：Journal of the International AIDS Society

authors： Kelly SL,Shattock AJ,Kerr CC,Stuart RM,Papoyan A,Grigoryan T,Hovhannisyan R,Grigoryan S,Benedikt C,Wilson DP

更新日期：2016-06-07 00:00:00